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Valine

Valine - Benefits, Deficiency Symptoms And Food Sources

Valine is an essential amino acid, which means that it cannot be manufactured in the body and must be obtained through dietary sources. It is one of several essential amino acids needed in the diet, as the human body cannot synthesize it from simpler metabolites. Valine contributes to the structure of proteins into which it has been incorporated by the tendency of its side chain to participate in hydrophobic interactions.

As such, their value in the formation and maintenance of structural and functional integrity in humans is unmeasured. Supplemental valine should always be combined with isoleucine and leucine at a respective milligram ratio of 2:1:2.

Functions and Benefits of Valine

Recent studies indicate that valine, as well as leucine and isoleucine, may be effective in treating or reversing hepatic encephalopathy or alcohol related brain damage. It may also be useful in degenerative neurological conditions. These essential amino acids work together and are classified as "branched-chain" amino acids. The three combine to regulate the protein turnover and energy metabolism, are stored in muscle tissue, and are released to be converted into energy during times of fasting or between meals.

Other topics of the continued research into valine supplementation include liver disease and the muscular degeneration in severe trauma patients, especially post-surgery and severe burn patients.

Recommended Dosage for Valine

As with all supplements and medications, it is necessary to consult your doctor for proper dosage. Most people do not require lysine supplementation. Adults may need up to 30 mg per kilogram of body weight per day. Typical dosage used for possible prevention of herpes simplex virus recurrence is 500 mg to 3 grams daily.

Food Sources of Valine

Valine can be found in soy proteins, meats, wheat, varagu, bajra, horse gram, peanuts, mushrooms, drumstick leaves, agathi, colocasia, beetroot, jack, French beans, gingelly seeds, linseed, banana, persimmon, and dairy products especially in cottage cheese.

Deficiency Symptoms of Valine

Valine deficiency results in negative hydrogen balance in the body, deterioration of muscle function and mental health, insomnia, and skin hypersensitivity. Low level of valine and other branched chain amino acids it can result in maple syrup urine disease. Some symptoms of valine deficiency include loss of balance during locomotion, changes in the ventral horn and susceptibility to irritation allergens.

 


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